difference between cerave retinol serums

The transformative ingredient is otherwise known as pure vitamin A. "But by pairing the two, you get the almost-instant hit of the retinol along with the longer-term action of the retinyl propionate," she explains, adding that this particular combo should reduce irritation and dryness. Related Post: Olay AHA + Peptide 24 Review. If skin irritation occurs, wash the product off and consult a physician. In addition to encapsulated retinol, this air-tight pump bottle is filled with ceramides to replenish and protect the skin barrier, plus hydrating humectants like hyaluronic acid and niacinamide. Pros. CeraVe Skin Renewing Retinol Serum is a great multi-tasking retinol serum that includes ceramides and niacinamide. 2 (0.3 percent retinol) and No. | Cruelty-Free: No | Byrdie Clean: No, Addition of green tea to retinol doubles down on antioxidants, Some reviewers note castor oil might be too thick. Bakuchi seed oil is the starring ingredient in this rich, concentrated cream. For more of our favorite, hard-working skin-care products, keep reading: Done reading? Courtesy of brand . "Vitamin C is healthy for the skin [but] isn't as effective in collagen synthesis and antiaging as retinol is.". This post contains affiliate links, and any purchases made through these links will result in a commission for me at no extra cost to you. 2014;36(3):221-230. doi: 10.1111/ics.12117, The 16 Best Over-the-Counter Retinols of 2023, The 20 Best Body Washes of 2023, Tested and Approved by Experts, The 11 Best Vitamin C Serums of 2023, Tested & Reviewed, The 16 Best Anti-Wrinkle Eye Creams of 2023, The 17 Best Face Creams for Dry Complexions of 2023, The 18 Best Eye Masks of 2023 To Combat Puffiness and Dark Circles, The 15 Best Moisturizers for Rosacea of 2023, These Acne Face Washes Are Your Ticket to Clearer Skin, The 16 Best Leave-in Conditioners for Curly Hair of 2023, The 15 Best Drugstore Night Creams of 2023. Electron physician. For instance, a publication in the Journal of Clinical and Aesthetic Dermatology, states that niacinamide can repair the skin barrier and improve skin moisture, as well as reduce inflammation, blotchiness, hyperpigmentation, acne, and wrinkling. Three types of ceramides (1, 3, and 6-II) meet encapsulated retinol for a serum that's not only hydrating and fortifying for the skin barrier, but is totally fragrance-free and ideal for. However, adapalene . Some have completely disappeared from my face and others have lightened significantly. Instead of retinol, Eau Thermale Avne's RetrinAL 0.1 Intensive Cream is formulated with its sibling, retinaldehyde, and the brand's Thermal Spring Water, which soothes and calms the skin in the event of irritation. Can be used on its own or layered with moisturisers. Although the amount of retinol is not disclosed, this retinoid serum is a good choice for those new to retinol since the formula lists retinol as low on the list of concentrated ingredients. How is retinol used? If youre looking for skincare products to address the signs of aging, we recommendCarrot & Stick. JAK POZBYAM SIE TRDZIKU czyli jak RETINOL z THE ORDINARY oczyci moj skr w 3 miesice Sub PURGING vs IRYTACJA skry po RETINOLU Jak pozby si trdziku. Karp also likes CeraVe's Skin Renewing Cream Serum. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. ", Active Ingredients: Retinol, vitamin C | Retinol Concentration: Not listed | Dosage: A few drops daily | Size: 1 oz | Cruelty-Free: Yes | Byrdie Clean: Yes. $26 at Amazon $29 at Ulta Beauty $23 at Walmart. Without ceramides, the skin barrier is weakened, just like without mortar a brick wall would be weak and unstable. To learn more or opt-out, visit, MVE Technology: Encapsulates ceramides to ensure efficient delivery within your skins barrier and slow release over time, supporting your protective skin barrier long after youve finished applying, Encapsulated retinol: Helps smooth fine lines and wrinkles, Three essential ceramides: That work together to lock in moisture and help restore your skins protective barrier, Hyaluronic acid: Helps retain your skins natural moisture, Apply Skin Renewing Retinol Serum in small dots where needed around your face, Gently smooth serum onto your skin until its thoroughly absorbed. This site is intended for US consumers. The Resurfacing Retinol Serum notably contains Licorice Root Extract which is known to be especially beneficial for those struggling with inflammation-related concerns such as acne and eczema. According to a publication in the journal. For similar reasons, Dr. King is also a fan of the Rejuveness Skin Tightening Serum. CeraVe Skin Renewing Retinol Serum. they both do not contain any common allergens or parabens. Olay Retinol 24 Max Night Hydrating Moisturizer is formulated with Olays retinoid complex containing retinol and retinyl propionate. 2014;71(1):177-184. doi: 10.1016/j.jaad.2014.01.891, Shin, Eun Ju et al. This product dries down quickly in about 15 seconds and totally absorbs into the skin. As an Amazon Associate, I earn from qualifying purchases. Clinical Interventions in Aging. This lightweight, fast-absorbing face serum, with encapsulated retinol and licorice root extract, helps brighten and resurface the skin. Bliss Youth Got This Pure Retinol Serum. oz. Since LOral products are sold in China, they must test their products on animals by law. This gentle yet constant delivery . References:1. The percentage of retinol is just enough to be effective in improving the appearance of fine lines, wrinkles, acne and pores, but has less potential to cause major irritation or dryness. Ask any dermatologist which one ingredient you should diligently apply in your skincare regime and they'll almost unanimously wax lyrical about retinol and the best retinol serums. Adapalene is way stronger, the cerave won't compare 21 BlueHybrid138 2 yr. ago adapalene is a retinoid, retinol has to undergo 2 reactions to be converted into retinoid. Non-irritating. As Dr. Madfes explains, it creates a firming effect by activating the retinoid receptors within our skin, which "stimulates collagen and elastin production. Cerave resurfacing retinol serum has. Moonlight Super Serum contains retinal (short for retinaldehyde), which is believed to be more effective than standard retinol but still plenty gentle. Ill compare Olays Retinol 24 cream and serum to CeraVes popular retinol serum: CeraVe Resurfacing Retinol Serum. "I typically recommend patients apply a moisturizer on top to alleviate any potential dryness," Dr. Kim adds. The dermatologist-recommended formula contains 1.5 percent encapsulated retinol, plus brightening antioxidants and moisturizing squalane. Use retinoids at night. 2015;37(5):519-525. doi: 10.1111/ics.12244, Mukherjee S, Date A, et al. Niacinamide and licorice root extract brighten and soothe the skin. CeraVe Retinol Face Serum For Post-Acne Marks vs. In a clinical trial commissioned by the brand, 100 percent of users noticed an improvement in their skin after just a week. We also like that the formula is safe for skin that's prone to acne, as castor oil is known not only for its antimicrobial and anti-inflammatory properties, but also for its ability to diminish the appearance of scars. This might be why its Amazons second best-selling face serum. Skin Renewing Retinol Serum. Case in point? Carrot & Stick intro bundles deliver great value for money because you can bundle 3 full-size products worth up to$240for $88. Massage one to two pumps every other night in an upwards motion (up to the jawline) and steadily increase usage if/when your skin can tolerate it. When applied to the skin, retinol is clinically proven to provide numerous benefits to the skin. If you have eczema, rosacea, or your skin is particularly sensitive, this can be a gentle way to ease into using retinol in your regimen. Active Ingredients: Retinol, ceramides | Retinol Concentration: Not listed | Dosage: One capsule nightly | Size: 30 capsules | Cruelty-Free: No | Byrdie Clean: Yes. The CeraVe Resurfacing Retinol face serum includes encapsulated retinol, which is simply retinol that has been housed in a delivery system to protect its integrity and improve its ability to penetrate into the skin effectively. 4.4. It's the more potent of the forms that are available without a prescription and when applied to the skin, it converts itself into retinoic acid. CeraVe Skin Renewing Cream Serum is a gentle yet effective daily Retinol cream Serum that provides a variety of anti-aging benefits. These natural chemicals work simultaneously with retinol's auxiliary exfoliating effect to uncover fresh layers of skin, essentially speeding up the skin's natural regeneration process and consequently thwarting any and every skin issue that springs to mind. Additionally, if you apply this serum during the day, its important to follow with a broad spectrum SPF 30 sunscreen and reapply every 2 hours or as much as your lifestyle allows. To minimize stinging and redness, opt for retinol serums containing soothing ingredients, such as chamomile, aloe, witch hazel, and green tea. 2016;8(9):3024-3031. doi: 10.19082/3024, Kim SJ, Baek JH, et al. Fig.1's Retinol Night Cream is ideal for beginners because it only contains a retinol level of 0.15 percent, making it super gentle (but effective) for those who are just starting out. While its star ingredient, retinyl retinoate, is less fierce than retinol, one study found it to be more effective at stimulating hyaluronan production than both retinol and retinoic acid. "I'm a fan of this Ayurvedic brand, and was thrilled when I discovered this retinol-alternative. It's one of a few vitamin A derivatives (aka retinoids) you can buy over the counter, often in the form of a serum. When applied to the skin, retinol is clinically proven to provide numerous benefits to the skin. "This makes it much more tolerable and decreases any redness or dryness. CeraVe's Skin Renewing Cream Serum helps reduce and prevent visible signs of aging using super-ingredients like retinol, niacinamide, ceramides and hyaluronic acid. CeraVe's Retinol Serum is a fan favorite for its refreshing feel and the way it helps firm skin without aggravating breakouts. CeraVe Anti Aging Retinol Serum | 1 Ounce | Cream Serum for Smoothing Fine Lines and Skin Brightening | Fragrance Free $20.99 $ 18.79 in stock . Michelle Regalado is a seasoned editor, fact-checker, and content strategist with expertise in women's lifestyle news. Amazon.com as of January 21, 2023 3:17 am . For an additional anti-aging boost, this moisturizer contains Olays amino peptide, palmitoyl pentapeptide-4. "It's an absolute game-changer. Do you need to wash retinol off in the morning? Unsurprisingly, though, they do happen to have a *lot* in common. What are the Best Skin Care Products of 2023? The Resurfacing range is intended for those with pigmentation and complexion-related concerns such as post-acne marks, dark spots, and enlarged pores, whereas the Skin Renewing range is intended for those looking for an anti-aging solution (e.g. Apart from retinol, of course, IT Cosmetics's Hello Results Wrinkle-Reducing Daily Retinol Serum-in-Cream is notable for also featuring "niacinamide, vitamin E, and panthenol to moisturize and soothe [the skin]," Dr. Turegano notes. 2009;14(1):540-554. doi: 10.3390/molecules14010540, Miraj S, Alesaeidi S. A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). CeraVe Skin Renewing Retinol Cream Serum. $19 at CeraVe. "Retinol regulates our sebum production, which is great for acne control," she adds. The Resurfacing Retinol Serum is better suited for those struggling with uneven skin tone and visible pores, whereas the Skin Renewing Retinol Serum is more for those looking to reduce the appearance of fine lines and wrinkles. they're both likely to be good for fighting acne, anti aging, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture. WITH MVE DELIVERY TECHNOLOGY Retinol is a vital nutrient. Cons. In a clinical trial, 100 percent of people noticed a reduction in fine lines and visibly firmer skin after just four weeks of using the ceramide-infused anti-ager. Serums contain higher concentrations of active ingredients, and since they're so thin and light, Dr. Van Dyke says, they penetrate skin more efficiently than creams. She covers skincare, haircare, and makeup at Byrdie. This fragrance-free nighttime formula is an ideal starter retinol, both for your retinoid-virgin skin and budget. The subtle orange creamsicle scent doesn't hurt, either. CeraVe has a store locator on their website so you can find a location near you. "It's important to apply sunscreen in the morning to protect and continue the collagen-stimulating benefits.". Designed for all skin types, this handy three-pack features a vitamin C serum to aid brightening, a retinol serum to help diminish lines and wrinkles, and a hyaluronic acid serum to boost hydration. Its non-comedogenic, paraben-free, and fragrance-free. CeraVe does not have a return policy on their website since they do not sell products on their website and, therefore, dont accept returns. Landing on a retinol that your skin won't reject takes patience and knowledge, but most of the latter's credit goes to the cosmetic chemists who've dreamed up innovative ways to deliver all the magic of this molecule without the cursed side effects. Putting on your moisturizer/night cream is supposed to prevent and/or soothe any bad reactions. With any retinoid, especially if you have sensitive skin, you have to practice restraint and apply a pea-size drop only one or two nights a week until your skin acclimates. As its name suggests, it is a hybrid product that's both serum and . Related Post: CeraVe vs Cetaphil: Which is Better? Although retinol products can improve the appearance of fine lines and wrinkles, and can also help to clear up acne, when you stop using the treatment, your skin will often return to baseline or pre-treatment condition. We rounded up standout options touted by dermatologists, as well as a few fan favorites from the Byrdie team. doi:10.3390/ijms20215262, Sarkar R, Arora P, Garg Kv. Learn more about, Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. A properly functioning stratum corneum is essential for healthy skin as it maintains epidermal hydration and serves as a barrier that responds to environmental stressors, infections, irritants, and allergens. This should lend some preliminary insight as to what we can expect when we dive into the specific differences between the formulas themselves. THIS SITE IS AFFILIATED WITH FORMULYST AND CARROT & STICK, WHOSE PRODUCTS ARE AMONG THOSE WE REVIEW AND RANK. Soothes the skin. It's a powerful ingredient that helps to unclog pores, stimulate collagen production, reduce fine lines, increase skin cell turnover, smooth skin, and even out pigmentation and discoloration. Clin Interv Aging. Olay Retinol 24 Max Night Hydrating Moisturizer, Olay Retinol 24 vs Neutrogena Rapid Wrinkle Repair, Olay Collagen Peptide 24 vs Regenerist Micro-Sculpting Cream, CeraVe Retinol Resurfacing vs Renewing Retinol Serum, CeraVe Hydrating Cleanser vs Foaming Cleanser, There is a possibility that retinol might be too strong for you if you have. Suspended in the mix are retinol and the vitamin-A derivative retinyl propionate. "Retinol products are not to be used while pregnant," Dr. Madfes tells Byrdie. 2010 Feb; 3(2): 2241. The stratum corneum is the outer layer of skin, which can be thought of as a brick and mortar system. Aqua/Water/Eau, Glycerin, Caprylic/Capric Triglyceride, Potassium Cetyl Phosphate, Hydrogenated Palm Glycerides, Polysorbate 20, Peg-40 Stearate, Cyclopentasiloxane, Hydroxyethylcellulose, Potassium Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Niacinamide, Isoceteth-10, Dimethicone/Vinyl Dimethicone Crosspolymer, Triethanolamine, Cetearyl Alcohol, Behentrimonium Methosulfate, Cichorium Intybus Root Extract / Chicory Root Extract, Lecithin, Retinol, Silica, Sodium Lauroyl Lactylate, Cholesterol, Phenoxyethanol, Tocopherol, Alcohol, Hydroxyacetophenone, Citric Acid, Hydrolyzed Hyaluronic Acid, Pentylene Glycol, Xanthan Gum, Phytosphingosine, Butyrospermum Parkii Butter / Shea Butter, Ethylhexylglycerin. Size: 1.0 oz. "It contains high levels of wound healers for acne lesions, anti-inflammatories, and antioxidants from botanical sources," she tells Byrdie. It has been shown to be just as effective for anti aging purposes. Two of the best options at the drugstore are Olay Retinol 24 Max Night Serum and CeraVe Resurfacing Retinol Serum. My skin is extremely sensitive and no breakouts for me. Positive CeraVe Resurfacing Retinol Serum reviews mention that the serum really does help to improve the appearance of scarring and dark spots. For post-acne marks & pores. CeraVe skin care products are also sold in physical retail locations throughout the United States, such as Walmart, Target, Walgreens, etc. Olay also includes Tropaeolum majus flower/leaf/stem extract in the moisturizer to support a healthy skin barrier, plus glycerin to moisturize the skin. 15 Oatmeal Skin-Care Products to Soothe Super-Sensitive Skin, 13 Best Vitamin C Creams to Help Reverse Dull, Textured Skin, This $38 Hydrating Mask Helps Soften My Forehead Lines. I purchased this for the purpose of reducing the look of acne scars and as I saw it was good for sensitive skin and included retinol, I was excited to try this. CeraVe Skin Renewing Retinol Serum is a gentle, yet effective daily retinol serum that provides your skin with a variety of anti-aging benefits. Developed with dermatologists, CeraVe Skin Renewing Retinol Face Cream Serum for Fine Lines and Wrinkles is designed to help diminish the appearance of fine lines and wrinkles while also helping to repair the protective skin barrier with 3 essential ceramides (1, 3 and 6-II). It contains Hydroxypinacolone Retinoate, an ingredient that provides similar benefits with less irritation. these products have a total of 12 ingredients in common. Retains skin's natural moisture. And, since they're grease-free, serums are a more desirable choice for those with oily or acneic skin. When it comes to tackling just about any skin problemfrom fine lines and dark spots to uneven texture and breakoutsretinol is where it's at. In general, and especially if your skin is oily or acne-prone, you'll want to pick a retinol product that is formulated for your skin type. In our extensive search for non-irritating retinols, we've discovered plenty of standouts that are at once ultra-effective yet gentle enough for the retinoid-intolerant. Key Ingredients: Retinol, vitamin E, castor oil, green tea | Dosage: Small dots twice per day | Size: 1 fl. Use of this site constitutes acceptance of our Well look at product ingredients and performance in this post on Olay Retinol 24 vs CeraVe Resurfacing Retinol Serum. SEE ON AMAZON. LEARN ABOUT BYRDIE'S EDITORIAL GUIDELINES, board-certified dermatologist Joshua Zeichner, Board-certified dermatologist Melissa K. Levin, MD, Board-certified dermatologist Julie Russak, MD, Encapsulation and controlled release of retinol from silicone particles for topical delivery, Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology, A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile), The effect of physically applied alpha hydroxyl acids on the skin pore and comedone, Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety, The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products, Quercetin Directly Targets JAK2 and PKC and Prevents UV-Induced Photoaging in Human Skin. Retinol A derivative of vitamin A, retinol helps promote your skin's natural exfoliation process, in turn refining and resurfacing the skin to improve the appearance of fine lines, wrinkles, texture and uneven tone. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. Since retinoids can cause dryness, Dr. Madfes says, "the trick is to create a balance to not dry the top layer of our skin." Our retinol face serum is formulated with ingredients likehyaluronic acidfor extra hydration,niacinamideto soothe, and three essentialceramides that work together to lock in moisture and help restore your skins protective barrier. CeraVe Retinol Face Serum For Post-Acne Marks. We always appreciate a skin-care product that incorporates UV protection, which is just one of the reasons why CeraVe's Skin Renewing Day Cream with Sunscreen has earned our stamp of approval. cerave resurfacing retinol serum rosacea Green Beauty, 14 Top Dermatologists Reveal Their Summer Skin-Care Routines , Geek & Gorgeous 101 A-Game 10 0.1% Retinal Serum VS Avene RetrinAL 0.1, CeraVe Acne Control Treatment Gel 1.35 oz, Murad Outsmart Acne Clarifying Treatment - 1.7 fl. Best for sensitive skin: SkinCeuticals C E Ferulic with 15% L-Ascorbic Acid. However, if you want something a bit more affordable, you can't go wrong with The Inkey List Retinol Serum, an award-winning formula containing two retinoids, squalane, and hyaluronic acid. What Are Some Alternatives To CeraVe Resurfacing Retinol Serum? Use Olay Retinol 24 Max Night Serum with a soothing non-retinol moisturizer. Niacinamide For example, one review says, Another disappointing cream for me. "When used consistently, we also see a decrease in sun damage in the top layers of our skin.". retailers. Whether you choose Retinol 24 MAX serum or moisturizer, these Olay retinol products contain two different retinoids, niacinamide, and a firming peptide, to address the signs of aging. Ideal for thirstier skin types, this rich, lightly-scented Murad Retinol Youth Renewal Night Cream hydrates with shea butter, squalane, and a pack of fatty alcohols. Want to know a fascinating fact about this antioxidant-enriched Verso Night Cream? This night cream also contains niacinamide, an anti-aging all-star that brightens the skin by interrupting melanin production. How often should you apply retinol serums? Okay is strictly anti aging and Cerave is anti acne and pore refining. CeraVe Resurfacing Retinol Serum and other CeraVe skin care products are not sold on the brands website. What's more, he says the gel-like consistency offers a cooling, depuffing effect. Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. However, these products use different formulas to treat similar skin concerns. This top-rated serum isn't just one serum; it's three for the delightedly affordable price of $20. The gentle serum can be. SkinCeuticals Tripeptide-R Neck Repair's 0.2 percent pure, slow-release retinol (to boost cell turnover), 2.5 percent tripeptide concentrate, and 5 percent glaucine (derived from yellow poppy seed) complex is specifically designed to treat signs of aging in the neck. Dr. Barbara Sturm The Good C Vitamin C Serum, $145 Pros: Lightweight, super nourishing, easy to blend, balances the skin, spa-like quality Cons: None. CeraVe Resurfacing Retinol Serum is a facial serum formulated specifically for those with post-acne marks, uneven skin tone, and visible pores. It resurfaces the skin to reduce the look of acne scars (due to post-inflammatory hyperpigmentation), visible pores, and uneven skin tone. 4.3 $19.99 / size: 1.0 oz. And adapalene at 0.1% is the only over-the-counter retinoid you can buy. Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. Well cover each of these ingredients in this section so youll know exactly how they affect your skin. The serum is lightweight and fast-absorbing and uses CeraVe's MVE Technology to continually release moisturizing ingredients for long-lasting hydration. Retinol is a vitamin A derivative that stimulates collagen production to strengthen the skin's foundation. "This strong serum is also packed with vitamins A, C, and E and olive leaf extract. Key Ingredients: Retinol, niacinamide, licorice root extract | Dosage: Small dots twice per day | Size: 1 fl. By penetrating deep beneath your epidermis (the outer layer of your skin) and neutralizing free radicals, retinol boosts your skin's production of elastin, collagen, and comedolytic agents. If your skin has become sensitized, dial down your routine to two steps: a gentle cleanser and a moisturizer, says Sandy Skotnicki, M.D., a dermatologist and the author of Beyond Soap. In addition, niacinamide has anti-inflammatory benefits and regulates sebum production. You wash your face, with your cleanser, put on your retinol, and then you put on your moisturizer/night cream. Active Ingredients: Encapsulated retinol, ceramides, hyaluronic acid, niacinamide | Retinol Concentration: Not listed | Dosage: Small amount daily | Size: 1 oz | Cruelty-Free: No | Byrdie Clean: No. Don't Mix: Vitamin C with retinol. Dr. Turegano also gives this product a thumb's up, noting that it's been shown to have comparable results to tretinoin 0.025% prescription cream.. CeraVe is owned by LOral, a company that tests on animals. Olay Retinol 24 Max Night Serum contains the same ingredients as Olay Retinol 24 Max Night Hydrating Moisturizer to target the signs of aging. Adapalene and retinol are both retinoids, but adapalene is not a retinol. If your skin is on the drier side, go with CeraVe (words to live by). . | Cruelty-Free: Yes | Byrdie Clean: Yes. Enhanced with three essential Ceramides, Hyaluronic Acid and Niacinamide to help restore the skin barrier, retain hydration and help sooth the skin. High quality serums, like those from CeraVe, are an effective way to deliver active and beneficial ingredients to skin in a lightweight formulation that can be layered with other products and wont block pores. CeraVe Resurfacing Retinol Serum is formulated with encapsulated retinol which releases slowly to minimize irritation. Higher concentrations generally provide faster, more noticeable results, but if you have particularly sensitive skin, a lower concentration may be best. We've all been there, don't worry! It's fat-soluble,. LOreal and CeraVe are committed to a future without tests on animals. The fragrance-free moisturizer glides onto your skin like silk. IT Cosmetics Hello Results Wrinkle-Reducing Daily Retinol Serum-in-Cream $69.

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difference between cerave retinol serums